The 49th annual Spring Flood Run takes place this weekend.

Thousands of motorcyclists are expected to cruise on both sides of the Mississippi River this weekend. On the Minnesota side, most of the riders will cruise between the Twin Cities and Winona. The Flood Run has been a charity event since twelve bikers from the Twin Cities rode to Winona to help the city in its fight against the flooding Mississippi River in 1965. Money raised by the official sponsors is donated to Gillette Children's Hospital in St.Paul.